To clear a single path, you pull the connecting piece away and let it go in midair- a quick work-around is:

1. while in design mode, zoom out and drag a selection box over the entire design map. this will select every artboard as opposed to command-A which merely selects all the content.

2. press command-x (ctrl-x) to cut. everything copies and disappears

3. press command-v (ctrl-v) to paste. everything re-appears, except the prototype wire is gone.

this is no excuse, though- this feature should maybe be reconsidered for higher priority. also, EYE DROPPER HOTKEY priority should also be pushed up. seriously though, how hard is it to add a hotkey for an existing function??

This is neccessary! I don't even know how to clear a single path!??

has this been solved yet?

I'm not sure where this would live in the main dropdown menu, but In the prototype mode, it would be particularly useful to remove ALL target links in one go so that you can start again.

Currently (unless I've missed it, you have to remove each target individually by selecting (none) from the targets menu.

This is so frustrating you can't just clear your prototype path and start fresh!

Menu item to remove prototype links from single, multiple or all artboards.

Yesterday I wanted to show a different path through the program. Today I want to show a new path, using different options and screen versions.

i had to copy all artboards to a new file...from design view...this is a needed option

Is this possible yet?!

I'd like to clear the wires one artboard at a time too. Sometimes I just want to orphan an artboard to take it out of linkage.

Definitely, being able to reset the wires would be great

Is there are any (one click)reset button for the prototype routes?
Because sometimes the routes have to be relink thanks, it would be save time.

Absolutely! My prototype has become quite complex and a reset would be ideal.