As a product manager, so far loving AXD & can't wait for few top feature requests like UI, Icon libraries etc. It has made prototyping so much faster.
I would recommend, if a Product manager or designer picks a certain design template such as iOS flat design or Android Material Design then recommend or suggest possible issues across web vs mobile design during design mode. For e.g. width or placement of a grid element that is responsive, recommend best practices in design mode based on the device selected.